Oxford Science Enterprises Holdings II Limited
Registered name: OXFORD SCIENCE ENTERPRISES HOLDINGS II LIMITED
Part of Oxford Science Enterprises PLC groupOxford Science Enterprises Holdings II Limited made £0 revenue and £243m profit in the year to 31 Dec 2025.
Oxford Science Enterprises Holdings II Limited’s revenue was £0 in the year to 31 Dec 2025, with £243m profit. The company is classified under “activities of venture and development capital companies” and is based in Oxford.
- Status
- Active
- Location
- Oxford, South East
- Age
- 1 yr · since 2025
- Type
- Private Limited Company
Pass-through vehicle. This looks like a holding, staffing or umbrella company. Its revenue and profit may largely pass through to or from other entities, so the figures may not reflect a standalone operating business. It is excluded from our opportunity lists.
Part of a group. The filing indicates this company sits within a group structure, so its results may depend on intra-group trading and it may be hard to replicate independently.
Key figures
Unusual figures. Profit is higher than revenue in this filing. That usually means investment income, dividends from subsidiaries or one-off gains — or a mis-tagged figure. Check the original filing before drawing conclusions.
Badges are automated estimates derived from the filed figures — not statements of fact about the company.
Financial history
| Year to | 31 Dec 2025 |
|---|---|
| Disclosure | Full P&L |
| Profit & loss | |
| Revenue (turnover) | £0 |
| Operating profit | £243m |
| Profit before tax | £243m |
| Profit after tax | £243m |
| Profit (best available) | £243m |
| Employees (average) | — |
| Ratios | |
| Profit margin | — |
| Balance sheet — indirect signals, not revenue | |
| Net assets | — |
| Source | Accounts · bulk data Sep 2026 |
How the business works
- Profit margin
- —
- Profit ÷ revenue.
- Gross margin
- —
- Gross profit ÷ revenue. High for software and services.
- Revenue per employee
- —
- Revenue ÷ average employees.
- Profit per employee
- —
- Profit ÷ average employees.
- Cash conversion
- —
- Cash generated from operations ÷ operating profit. Needs a cash-flow statement.
- Fixed assets ÷ revenue
- —
- Capital intensity. Low = capital-light, cheaper to start.
- Deferred income ÷ revenue
- —
- Customers paying upfront (subscriptions, deposits). Approximate when combined with accruals.
- Debtors ÷ revenue
- —
- Money owed by customers. Low = customers pay quickly.
Balance-sheet signals
Year-on-year changes in filed balance-sheet items. They can hint at momentum (or investment) but are not revenue or profit and must not be read as such.
- Net assets
- —
- Now —
- Cash at bank
- —
- Now —
- Headcount
- —
- Now —
- Deferred income
- —
- Now —
- Fixed assets
- —
- Now —
Group structure
Ownership chain
- Oxford Science Enterprises PLCultimate parent75–100%
- Oxford Science Enterprises Holdings II Limitedthis company
Bands show the share of ownership each company holds in the one below it.
Sister companies (17)
- Acionna Therapeutics LtdFigures not disclosed
- Alethio Therapeutics LimitedFigures not disclosed
- Animal Dynamics LimitedRev. — · Profit −£195k
- Circadian Therapeutics LimitedFigures not disclosed
- Credo Therapies LtdFigures not disclosed
- Dyna Therapeutics LimitedFigures not disclosed
- Isogenix LimitedFigures not disclosed
- Kodiform Therapeutics LimitedFigures not disclosed
- Matchbio LimitedFigures not disclosed
- Nuanced Bio LtdFigures not disclosed
- Orfonyx Bio LtdFigures not disclosed
- Ose Labs LimitedFigures not disclosed
- Ose Manager LimitedFigures not disclosed
- Osi Midco LimitedFigures not disclosed
- Oxford Science Enterprises Holdings III LimitedFigures not disclosed
- Oxford Science Enterprises Holdings LimitedFigures not disclosed
- Thelior Bio LimitedFigures not disclosed
From the Persons with Significant Control register (corporate controllers only).
Sources
Latest figures from accounts for the year to 31 Dec 2025 (profit £243m), from the Companies House accounts bulk data published Sep 2026. Spotted an error? Request a correction.
Updated from Companies House on 11 Oct 2026
Contains public sector information from Companies House licensed under the Open Government Licence v3.0. Data from Companies House, © Crown copyright. View the licence.